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Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3198371

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

About this item

Full title

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.17450-17455

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Antiangiogenic therapy can produce transient tumor regression in glioblastoma (GBM), but no prolongation in patient survival has been achieved. We have constructed a nanosystem targeted to tumor vasculature that incorporates three elements: (i) a tumor-homing peptide that specifically delivers its payload to the mitochondria of tumor endothelial ce...

Alternative Titles

Full title

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3198371

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3198371

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1114518108

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