Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
About this item
Full title
Author / Creator
Mardis, Elaine R , Ding, Li , Dooling, David J , Larson, David E , McLellan, Michael D , Chen, Ken , Koboldt, Daniel C , Fulton, Robert S , Fulton, Lucinda A , Delehaunty, Kim D , McGrath, Sean D , Locke, Devin P , Magrini, Vincent J , Abbott, Rachel M , Vickery, Tammi L , Reed, Jerry S , Robinson, Jody S , Wylie, Todd , Smith, Scott M , Carmichael, Lynn , Eldred, James M , Harris, Christopher C , Walker, Jason , Peck, Joshua B , Du, Feiyu , Dukes, Adam F , Sanderson, Gabriel E , Brummett, Anthony M , Clark, Eric , McMichael, Joshua F , Meyer, Rick J , Schindler, Jonathan K , Pohl, Craig S , Wallis, John W , Shi, Xiaoqi , Lin, Ling , Schmidt, Heather , Tang, Yuzhu , Haipek, Carrie , Wiechert, Madeline E , Ivy, Jolynda V , Kalicki, Joelle , Elliott, Glendoria , Ries, Rhonda E , Payton, Jacqueline E , Westervelt, Peter , Tomasson, Michael H , Watson, Mark A , Baty, Jack , Heath, Sharon , Shannon, William D , Nagarajan, Rakesh , Link, Daniel C , Walter, Matthew J , Graubert, Timothy A , DiPersio, John F , Wilson, Richard K and Ley, Timothy J
Publisher
Waltham, MA: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Waltham, MA: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
A comparison of the genomic sequence of a tumor sample from a patient with acute myeloid leukemia (AML) and that of a normal skin sample from the same patient revealed an estimated 750 somatic mutations, of which 12 were in the coding sequences of genes and 52 were in conserved regions or regions with regulatory potential. Four mutations were found...
Alternative Titles
Full title
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
Authors, Artists and Contributors
Author / Creator
Ding, Li
Dooling, David J
Larson, David E
McLellan, Michael D
Chen, Ken
Koboldt, Daniel C
Fulton, Robert S
Fulton, Lucinda A
Delehaunty, Kim D
McGrath, Sean D
Locke, Devin P
Magrini, Vincent J
Abbott, Rachel M
Vickery, Tammi L
Reed, Jerry S
Robinson, Jody S
Wylie, Todd
Smith, Scott M
Carmichael, Lynn
Eldred, James M
Harris, Christopher C
Walker, Jason
Peck, Joshua B
Du, Feiyu
Dukes, Adam F
Sanderson, Gabriel E
Brummett, Anthony M
Clark, Eric
McMichael, Joshua F
Meyer, Rick J
Schindler, Jonathan K
Pohl, Craig S
Wallis, John W
Shi, Xiaoqi
Lin, Ling
Schmidt, Heather
Tang, Yuzhu
Haipek, Carrie
Wiechert, Madeline E
Ivy, Jolynda V
Kalicki, Joelle
Elliott, Glendoria
Ries, Rhonda E
Payton, Jacqueline E
Westervelt, Peter
Tomasson, Michael H
Watson, Mark A
Baty, Jack
Heath, Sharon
Shannon, William D
Nagarajan, Rakesh
Link, Daniel C
Walter, Matthew J
Graubert, Timothy A
DiPersio, John F
Wilson, Richard K
Ley, Timothy J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3201812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3201812
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa0903840
