Direct observation of disulfide isomerization in a single protein
Direct observation of disulfide isomerization in a single protein
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Photochemical uncaging techniques use light to release active molecules from otherwise inert compounds. Here we expand this class of techniques by demonstrating the mechanical uncaging of a reactive species within a single protein. We proved this novel technique by capturing the regiospecific reaction between a thiol and a vicinal disulfide bond. W...
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Full title
Direct observation of disulfide isomerization in a single protein
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3205468
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3205468
Other Identifiers
ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.1155
