CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
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London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Monocyte recruitment in metastasis
Macrophages are abundant in tumours, where they promote tumorigenesis and metastasis. Jeffrey Pollard and colleagues now identify inflammatory monocytes as a precursor population for the macrophages that promote breast cancer metastasis to the lung or bone. These cells are recruited through the cytokine CCL2 an...
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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3208506
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3208506
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10138
