Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan...
Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Endothelins are involved in tissue inflammation, pain, edema and cell migration. Our genome-wide microarray analysis revealed that endothelin-1 (ET-1) and endothelin-2 (ET-2) showed a marked up-regulation in dorsal root ganglia during the acute phase of arthritis. We therefore examined the effects of endothelin receptor antagonists on the developme...
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Full title
Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3218912
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3218912
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ISSN
1478-6354
E-ISSN
1478-6362,1478-6354
DOI
10.1186/ar3372
