Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for...
Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome
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Publisher
New York: Springer-Verlag
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Language
English
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Publisher
New York: Springer-Verlag
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Contents
Down syndrome (DS) is the most frequent genetic disorder leading to intellectual disabilities and is caused by three copies of human chromosome 21. Mouse models are widely used to better understand the physiopathology in DS or to test new therapeutic approaches. The older and the most widely used mouse models are the trisomic Ts65Dn and the Ts1Cje...
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Full title
Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling down syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3224224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3224224
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ISSN
0938-8990
E-ISSN
1432-1777
DOI
10.1007/s00335-011-9356-0
