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BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3230375

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

About this item

Full title

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2011-11, Vol.30 (21), p.4465-4478

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Both autophagy and apoptosis are tightly regulated processes playing a central role in tissue homeostasis. Bax inhibitor 1 (BI‐1) is a highly conserved protein with a dual role in apoptosis and endoplasmic reticulum (ER) stress signalling through the regulation of the ER stress sensor inositol requiring kinase 1 α (IRE1α). Here, we describe a novel...

Alternative Titles

Full title

BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3230375

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3230375

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2011.318

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