Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endosta...
Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production
About this item
Full title
Author / Creator
Fukuda, H , Mochizuki, S , Abe, H , Okano, H J , Hara-Miyauchi, C , Okano, H , Yamaguchi, N , Nakayama, M , D'Armiento, J and Okada, Y
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Background:
Although matrix metalloproteinases (MMPs) are implicated in tumourigenesis and cancer progression, the role of MMP-13 in melanoma cell metastases is poorly understood.
Methods:
Lung metastases of mouse melanoma B16BL6 cells were analysed in MMP-13 knockout (KO) and wild-type (WT) mice after intravenous injection. The mRNA and p...
Alternative Titles
Full title
Host-derived MMP-13 exhibits a protective role in lung metastasis of melanoma cells by local endostatin production
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3242531
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3242531
Other Identifiers
ISSN
0007-0920
E-ISSN
1532-1827
DOI
10.1038/bjc.2011.431
