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FGF signalling inhibits neural induction in human embryonic stem cells

FGF signalling inhibits neural induction in human embryonic stem cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3243624

FGF signalling inhibits neural induction in human embryonic stem cells

About this item

Full title

FGF signalling inhibits neural induction in human embryonic stem cells

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2011-12, Vol.30 (24), p.4874-4884

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Human embryonic stem cells (hESCs) can exit the self‐renewal programme, through the action of signalling molecules, at any given time and differentiate along the three germ layer lineages. We have systematically investigated the specific roles of three signalling pathways, TGFβ/SMAD2, BMP/SMAD1, and FGF/ERK, in promoting the transition of hESCs int...

Alternative Titles

Full title

FGF signalling inhibits neural induction in human embryonic stem cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3243624

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3243624

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2011.407

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