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Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3257393

Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

About this item

Full title

Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2012-05, Vol.31 (21), p.2653-2667

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Dysregulation of β-catenin turnover due to mutations of its regulatory proteins including adenomatous polyposis coli (APC) and p53 is implicated in the pathogenesis of cancer. Thus, intensive effort is being made to search for alternative approaches to reduce abnormally activated β-catenin in cancer cells. Nur77, an orphan member of the nuclear rec...

Alternative Titles

Full title

Inhibition of β-catenin signaling by nongenomic action of orphan nuclear receptor Nur77

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3257393

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3257393

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2011.448

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