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Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3261559

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

About this item

Full title

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

Publisher

Chichester, UK: John Wiley & Sons, Ltd

Journal title

The EMBO journal, 2012-01, Vol.31 (2), p.378-390

Language

English

Formats

Publication information

Publisher

Chichester, UK: John Wiley & Sons, Ltd

More information

Scope and Contents

Contents

Covalent modification of proteins with ubiquitin (Ub) is widely implicated in the control of protein function and fate. Over 100 deubiquitylating enzymes rapidly reverse this modification, posing challenges to the biochemical and biophysical characterization of ubiquitylated proteins. We circumvented this limitation with a synthetic biology approac...

Alternative Titles

Full title

Synthetic biology approach to reconstituting the ubiquitylation cascade in bacteria

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3261559

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3261559

Other Identifiers

ISSN

0261-4189

E-ISSN

1460-2075

DOI

10.1038/emboj.2011.397

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