VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
About this item
Full title
Author / Creator
De Stefani, D , Bononi, A , Romagnoli, A , Messina, A , De Pinto, V , Pinton, P and Rizzuto, R
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Voltage-dependent anion channels (VDACs) are expressed in three isoforms, with common channeling properties and different roles in cell survival. We show that VDAC1 silencing potentiates apoptotic challenges, whereas VDAC2 has the opposite effect. Although all three VDAC isoforms are equivalent in allowing mitochondrial Ca
2+
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Alternative Titles
Full title
VDAC1 selectively transfers apoptotic Ca2+ signals to mitochondria
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3263501
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3263501
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2011.92
