The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin–associated hemolytic ur...
The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin–associated hemolytic uremic syndrome in humans and mice
About this item
Full title
Author / Creator
Petruzziello-Pellegrini, Tania N. , Yuen, Darren A. , Page, Andrea V. , Patel, Sajedabanu , Soltyk, Anna M. , Matouk, Charles C. , Wong, Dennis K. , Turgeon, Paul J. , Fish, Jason E. , Ho, J.J. David , Steer, Brent M. , Khajoee, Vahid , Tigdi, Jayesh , Lee, Warren L. , Motto, David G. , Advani, Andrew , Gilbert, Richard E. , Karumanchi, S. Ananth , Robinson, Lisa A. , Tarr, Phillip I. , Liles, W. Conrad , Brunton, James L. and Marsden, Philip A.
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Hemolytic uremic syndrome (HUS) is a potentially life-threatening condition. It often occurs after gastrointestinal infection with E. coli O157:H7, which produces Shiga toxins (Stx) that cause hemolytic anemia, thrombocytopenia, and renal injury. Stx-mediated changes in endothelial phenotype have been linked to the pathogenesis of HUS. Here we repo...
Alternative Titles
Full title
The CXCR4/CXCR7/SDF-1 pathway contributes to the pathogenesis of Shiga toxin–associated hemolytic uremic syndrome in humans and mice
Authors, Artists and Contributors
Author / Creator
Yuen, Darren A.
Page, Andrea V.
Patel, Sajedabanu
Soltyk, Anna M.
Matouk, Charles C.
Wong, Dennis K.
Turgeon, Paul J.
Fish, Jason E.
Ho, J.J. David
Steer, Brent M.
Khajoee, Vahid
Tigdi, Jayesh
Lee, Warren L.
Motto, David G.
Advani, Andrew
Gilbert, Richard E.
Karumanchi, S. Ananth
Robinson, Lisa A.
Tarr, Phillip I.
Liles, W. Conrad
Brunton, James L.
Marsden, Philip A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3266777
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3266777
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI57313
