Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice
Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice
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Author / Creator
Weissmann, Norbert , Sydykov, Akylbek , Kalwa, Hermann , Storch, Ursula , Fuchs, Beate , Mederos y Schnitzler, Michael , Brandes, Ralf P. , Grimminger, Friedrich , Meissner, Marcel , Freichel, Marc , Offermanns, Stefan , Veit, Florian , Pak, Oleg , Krause, Karl-Heinz , Schermuly, Ralph T. , Brewer, Alison C , Schmidt, Harald H.H.W. , Seeger, Werner , Shah, Ajay M. , Gudermann, Thomas , Ghofrani, Hossein A. and Dietrich, Alexander
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Lung ischaemia–reperfusion-induced oedema (LIRE) is a life-threatening condition that causes pulmonary oedema induced by endothelial dysfunction. Here we show that lungs from mice lacking nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (
Nox2
y/−
) or the classical transient receptor potential channel 6 (
TRPC6
−/−
) a...
Alternative Titles
Full title
Activation of TRPC6 channels is essential for lung ischaemia–reperfusion induced oedema in mice
Authors, Artists and Contributors
Author / Creator
Sydykov, Akylbek
Kalwa, Hermann
Storch, Ursula
Fuchs, Beate
Mederos y Schnitzler, Michael
Brandes, Ralf P.
Grimminger, Friedrich
Meissner, Marcel
Freichel, Marc
Offermanns, Stefan
Veit, Florian
Pak, Oleg
Krause, Karl-Heinz
Schermuly, Ralph T.
Brewer, Alison C
Schmidt, Harald H.H.W.
Seeger, Werner
Shah, Ajay M.
Gudermann, Thomas
Ghofrani, Hossein A.
Dietrich, Alexander
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3272568
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3272568
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms1660
