Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques
Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Transgenic macaques would allow to study brain function and diseases. We report that an engineered adeno-associated virus serotype 9 variant (scAAV9) injected intravenously in newborn rhesus macaques results in efficient, exclusively-neuronal and widespread transduction of the brain. The present data pave the way to large-scale genetic modelling of...
Alternative Titles
Full title
Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3275921
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3275921
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep00253
