DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenua...
DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Scope and Contents
Contents
Highlights ► Can vaccine for Alzheimer's disease (AD) be effective at the onset of the disease? ► Vaccine use in old mice ameliorates cognitive AD impairments. ► Vaccine provides survival benefit and prolongs life span of AD mice.
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Full title
DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3278568
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3278568
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2011.12.136