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DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenua...

DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenua...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3278568

DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease

About this item

Full title

DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2012-02, Vol.30 (9), p.1650-1658

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights ► Can vaccine for Alzheimer's disease (AD) be effective at the onset of the disease? ► Vaccine use in old mice ameliorates cognitive AD impairments. ► Vaccine provides survival benefit and prolongs life span of AD mice.

Alternative Titles

Full title

DNA immunization with HBsAg-based particles expressing a B cell epitope of amyloid β-peptide attenuates disease progression and prolongs survival in a mouse model of Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3278568

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3278568

Other Identifiers

ISSN

0264-410X

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2011.12.136

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