Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced sene...
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Telomeres are specialized nucleoprotein structures, which protect chromosome ends and have been implicated in the ageing process. Telomere shortening has been shown to contribute to a persistent DNA damage response (DDR) during replicative senescence, the irreversible loss of division potential of somatic cells. Similarly, persistent DDR foci can b...
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Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3292717
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3292717
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms1708
