A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
About this item
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Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
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Scope and Contents
Contents
Surface‐exposed calreticulin (ecto‐CRT) and secreted ATP are crucial damage‐associated molecular patterns (DAMPs) for immunogenic apoptosis. Inducers of immunogenic apoptosis rely on an endoplasmic reticulum (ER)‐based (reactive oxygen species (ROS)‐regulated) pathway for ecto‐CRT induction, but the ATP secretion pathway is unknown. We found that a...
Alternative Titles
Full title
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3298003
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3298003
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2011.497
