The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53
The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The orphan nuclear receptor TR3 (NR41A and Nur77) is overexpressed in most lung cancer patients and is a negative prognostic factor for patient survival. The function of TR3 was investigated in non-small-cell lung cancer A549 and H460 cells, and knockdown of TR3 by RNA interference (siTR3) inhibited cancer cell growth and induced apoptosis. The pro...
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Full title
The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3299891
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3299891
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/onc.2011.504
