Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertroph...
Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin
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Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
Journal title
Language
English
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Publication information
Publisher
Cairo, Egypt: Hindawi Puplishing Corporation
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Scope and Contents
Contents
Microfabricated thermoelectric controllers can be employed to investigate mechanisms underlying myosin-driven sliding of Ca2+-regulated actin and disease-associated mutations in myofilament proteins. Specifically, we examined actin filament sliding—with or without human cardiac troponin (Tn) and α-tropomyosin (Tm)—propelled by rabbit skeletal heavy...
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Full title
Micromechanical Thermal Assays of Ca2+-Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3303698
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3303698
Other Identifiers
ISSN
1110-7243
E-ISSN
1110-7251
DOI
10.1155/2012/657523
