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Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis

Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3306694

Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis

About this item

Full title

Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (11), p.4263-4268

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Hyaluronic acid (HA) has been implicated in the proliferation and metastasis of tumor cells. However, most previous studies were conducted on extracellular matrix or pericellular HA, and the role of circulating HA in vivo has not been studied. HA is rapidly cleared from the bloodstream. The scavenger receptor Stabilin-2 (Stab2) is considered a majo...

Alternative Titles

Full title

Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3306694

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3306694

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1117560109

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