Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis
Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Hyaluronic acid (HA) has been implicated in the proliferation and metastasis of tumor cells. However, most previous studies were conducted on extracellular matrix or pericellular HA, and the role of circulating HA in vivo has not been studied. HA is rapidly cleared from the bloodstream. The scavenger receptor Stabilin-2 (Stab2) is considered a majo...
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Full title
Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3306694
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3306694
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1117560109