Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
About this item
Full title
Author / Creator
Jäger, Stefanie , Kim, Dong Young , Hultquist, Judd F. , Shindo, Keisuke , LaRue, Rebecca S. , Kwon, Eunju , Li, Ming , Anderson, Brett D. , Yen, Linda , Stanley, David , Mahon, Cathal , Kane, Joshua , Franks-Skiba, Kathy , Cimermancic, Peter , Burlingame, Alma , Sali, Andrej , Craik, Charles S. , Harris, Reuben S. , Gross, John D. and Krogan, Nevan J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The transcription cofactor CBF-β is shown to regulate the ability of HIV-1 to evade host restriction mediated by the deaminase APOBEC3; it acts by interacting with the HIV protein Vif, so disrupting the Vif–CBF-β interaction could provide a new therapeutic target against HIV-1 infection.
Vif–CBF-β interaction an anti-HIV-1 target
The transcri...
Alternative Titles
Full title
Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection
Authors, Artists and Contributors
Author / Creator
Kim, Dong Young
Hultquist, Judd F.
Shindo, Keisuke
LaRue, Rebecca S.
Kwon, Eunju
Li, Ming
Anderson, Brett D.
Yen, Linda
Stanley, David
Mahon, Cathal
Kane, Joshua
Franks-Skiba, Kathy
Cimermancic, Peter
Burlingame, Alma
Sali, Andrej
Craik, Charles S.
Harris, Reuben S.
Gross, John D.
Krogan, Nevan J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3310910
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3310910
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10693
