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APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314181

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

About this item

Full title

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Publisher

Basel: SP Birkhäuser Verlag Basel

Journal title

Cellular and molecular life sciences : CMLS, 2012-04, Vol.69 (8), p.1353-1375

Language

English

Formats

Publication information

Publisher

Basel: SP Birkhäuser Verlag Basel

More information

Scope and Contents

Contents

The amyloid precursor protein (APP) is part of a larger gene family, which has been found to form homo- or heterotypic complexes with its homologues, whereby the exact molecular mechanism and origin of dimer formation remains elusive. In order to assess the cellular location of dimerization, we have generated a cell culture model system in CHO-K1 c...

Alternative Titles

Full title

APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314181

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314181

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-011-0882-4

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