APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms
APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms
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Basel: SP Birkhäuser Verlag Basel
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Language
English
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Publisher
Basel: SP Birkhäuser Verlag Basel
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Contents
The amyloid precursor protein (APP) is part of a larger gene family, which has been found to form homo- or heterotypic complexes with its homologues, whereby the exact molecular mechanism and origin of dimer formation remains elusive. In order to assess the cellular location of dimerization, we have generated a cell culture model system in CHO-K1 c...
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Full title
APP dimer formation is initiated in the endoplasmic reticulum and differs between APP isoforms
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314181
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3314181
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ISSN
1420-682X
E-ISSN
1420-9071
DOI
10.1007/s00018-011-0882-4