Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia
Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia
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Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
David Mitchell, Hannah Mitchison and colleagues identify a new
Chlamydomonas
protein required for the preassembly of axonemal dyneins before their transport into cilia. They further show that mutations in the homologous gene in humans result in primary ciliary dyskinesia accompanied by defects in the assembly of inner and outer dynein arms.
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Full title
Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3315610
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3315610
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.1106
