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IL-4 Determines Eicosanoid Formation in Dendritic Cells by Down-Regulation of 5-Lipoxygenase and Up-...

IL-4 Determines Eicosanoid Formation in Dendritic Cells by Down-Regulation of 5-Lipoxygenase and Up-...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_33179

IL-4 Determines Eicosanoid Formation in Dendritic Cells by Down-Regulation of 5-Lipoxygenase and Up-Regulation of 15-Lipoxygenase 1 Expression

About this item

Full title

IL-4 Determines Eicosanoid Formation in Dendritic Cells by Down-Regulation of 5-Lipoxygenase and Up-Regulation of 15-Lipoxygenase 1 Expression

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2001-04, Vol.98 (9), p.5152-5157

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Dendritic cell (DC) differentiation from human CD34+hematopoietic progenitor cells (HPCs) can be triggered in vitro by a combination of cytokines consisting of stem cell factor, granulocytemacrophage colony-stimulating factor, and tumor necrosis factor α. The immune response regulatory cytokines, IL-4 and IL-13, promote DC maturation from HPCs, ind...

Alternative Titles

Full title

IL-4 Determines Eicosanoid Formation in Dendritic Cells by Down-Regulation of 5-Lipoxygenase and Up-Regulation of 15-Lipoxygenase 1 Expression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_33179

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_33179

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.091076998

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