Wild-type microglia arrest pathology in a mouse model of Rett syndrome
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Transplanting bone marrow from wild-type mice into MECP2-lacking mice results in wild-type microglial engraftment, extends lifespan and reduces symptoms of disease such as breathing and locomotor abnormalities, implicating microglia in the pathophysiology of Rett syndrome.
Marrow implants in Rett syndrome
The X-linked autism spectrum disorder...
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Full title
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3321067
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3321067
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature10907
