Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of...
Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure
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Publisher
Basingstoke: Elsevier Inc
Journal title
Language
English
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Publisher
Basingstoke: Elsevier Inc
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Contents
Retinoic acid decreases proteinuria and glomerulosclerosis in several animal models of kidney disease by protecting podocytes from injury. Our recent in vitro studies suggest that all-trans retinoic acid induces podocyte differentiation by activating the retinoic acid receptor-α (RARα)/cAMP/PKA/CREB pathway. When used in combination with all-trans...
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Full title
Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3326224
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3326224
Other Identifiers
ISSN
0085-2538
E-ISSN
1523-1755
DOI
10.1038/ki.2011.467
