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The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3326235

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

About this item

Full title

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

European journal of nuclear medicine and molecular imaging, 2012-05, Vol.39 (5), p.811-823

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Purpose
In recent years there has been an increase in the development of radioligands targeting the 18-kDa translocator protein (TSPO). TSPO expression is well documented in activated microglia and serves as a biomarker for imaging neuroinflammation. In addition, TSPO has also been reported to be overexpressed in a number of cancer cell lines an...

Alternative Titles

Full title

The translocator protein ligand [18F]DPA-714 images glioma and activated microglia in vivo

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3326235

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3326235

Other Identifiers

ISSN

1619-7070

E-ISSN

1619-7089

DOI

10.1007/s00259-011-2041-4

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