Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-Bromopyruvate Prop...
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-Bromopyruvate Propyl Ester
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Author / Creator
Tang, Zhenjie , Yuan, Shuqiang , Hu, Yumin , Zhang, Hui , Wu, Wenjing , Zeng, Zhaolei , Yang, Jing , Yun, Jingping , Xu, Ruihua and Huang, Peng
Publisher
Boston: Springer US
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Language
English
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Publisher
Boston: Springer US
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Contents
It has long been observed that many cancer cells exhibit increased aerobic glycolysis and rely more on this pathway to generate ATP and metabolic intermediates for cell proliferation. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key enzyme in glycolysis and has been known as a housekeeping molecule. In the present study, we found that GAPD...
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Full title
Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-Bromopyruvate Propyl Ester
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3332040
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3332040
Other Identifiers
ISSN
0145-479X
E-ISSN
1573-6881
DOI
10.1007/s10863-012-9420-9