Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
About this item
Full title
Author / Creator
He, B Julie , Joiner, Mei-ling A , Singh, Madhu V , Luczak, Elizabeth D , Swaminathan, Paari Dominic , Koval, Olha M , Kutschke, William , Allamargot, Chantal , Yang, Jinying , Guan, Xiaoqun , Zimmerman, Kathy , Grumbach, Isabella M , Weiss, Robert M , Spitz, Douglas R , Sigmund, Curt D , Blankesteijn, W Matthijs , Heymans, Stephane , Mohler, Peter J and Anderson, Mark E
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
The hormone aldosterone can damage the heart after myocardial infarction, such that drugs that inhibit its action are often prescribed. B. Julie He
et al
. now uncover a new pathway underlying the detrimental effects of aldosterone action: oxidation of the enzyme Ca
2+
/calmodulin-dependent protein kinase II leads to its activation and...
Alternative Titles
Full title
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone
Authors, Artists and Contributors
Author / Creator
Joiner, Mei-ling A
Singh, Madhu V
Luczak, Elizabeth D
Swaminathan, Paari Dominic
Koval, Olha M
Kutschke, William
Allamargot, Chantal
Yang, Jinying
Guan, Xiaoqun
Zimmerman, Kathy
Grumbach, Isabella M
Weiss, Robert M
Spitz, Douglas R
Sigmund, Curt D
Blankesteijn, W Matthijs
Heymans, Stephane
Mohler, Peter J
Anderson, Mark E
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3332099
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3332099
Other Identifiers
ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm.2506
