Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis
Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis
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United States: American Society for Clinical Investigation
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Language
English
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Publisher
United States: American Society for Clinical Investigation
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Contents
Cooperativity between oncogenic mutations is recognized as a fundamental feature of malignant transformation, and it may be mediated by synergistic regulation of the expression of pro- and antitumorigenic target genes. However, the mechanisms by which oncogenes and tumor suppressors coregulate downstream targets and pathways remain largely unknown....
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Full title
Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3336973
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3336973
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ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI58540