NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Contents
In this study, the authors show that NgR1 and NgR3 can act as functional receptors for chondroitin sulfate proteoglycans (CSPGs), mediating inhibition of axonal growth and regeneration. This suggests a convergent mechanism for CSPG- and myelin-associated inhibitor activities after axonal injury in the CNS.
In the adult mammalian CNS, chondroitin...
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Full title
NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3337880
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3337880
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ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3070