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A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3337962

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

About this item

Full title

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Publisher

New York: Nature Publishing Group US

Journal title

Nature neuroscience, 2012-05, Vol.15 (5), p.793-802

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

This study describes the generation of knock-in mouse lines that express optogenetic activators or silencers in a CRE recombinase–dependent manner, and demonstrates the reliability and utility of these tools with
in vivo
and
ex vivo
light-induced activation and silencing of neuronal activity.
Cell type–specific expression of optogene...

Alternative Titles

Full title

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3337962

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3337962

Other Identifiers

ISSN

1097-6256

E-ISSN

1546-1726

DOI

10.1038/nn.3078

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