Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versu...
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages
About this item
Full title
Author / Creator
Schroder, Kate , Irvine, Katharine M. , Taylor, Martin S. , Bokil, Nilesh J. , Le Cao, Kim-Anh , Masterman, Kelly-Anne , Labzin, Larisa I. , Semple, Colin A. , Kapetanovic, Ronan , Fairbairn, Lynsey , Akalin, Altuna , Faulkner, Geoffrey J. , Baillie, John Kenneth , Gongora, Milena , Daub, Carsten O. , Kawaji, Hideya , McLachlan, Geoffrey J. , Goldman, Nick , Grimmond, Sean M. , Carninci, Piero , Suzuki, Harukazu , Hayashizaki, Yoshihide , Lenhard, Boris , Hume, David A. and Sweet, Matthew J.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Evolutionary change in gene expression is generally considered to be a major driver of phenotypic differences between species. We investigated innate immune diversification by analyzing interspecies differences in the transcriptional responses of primary human and mouse macrophages to the Toll-like receptor (TLR)–4 agonist lipopolysaccharide (LPS)....
Alternative Titles
Full title
Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages
Authors, Artists and Contributors
Author / Creator
Irvine, Katharine M.
Taylor, Martin S.
Bokil, Nilesh J.
Le Cao, Kim-Anh
Masterman, Kelly-Anne
Labzin, Larisa I.
Semple, Colin A.
Kapetanovic, Ronan
Fairbairn, Lynsey
Akalin, Altuna
Faulkner, Geoffrey J.
Baillie, John Kenneth
Gongora, Milena
Daub, Carsten O.
Kawaji, Hideya
McLachlan, Geoffrey J.
Goldman, Nick
Grimmond, Sean M.
Carninci, Piero
Suzuki, Harukazu
Hayashizaki, Yoshihide
Lenhard, Boris
Hume, David A.
Sweet, Matthew J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3341041
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3341041
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1110156109
