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Geometry sensing by dendritic cells dictates spatial organization and PGE₂-induced dissolution of po...

Geometry sensing by dendritic cells dictates spatial organization and PGE₂-induced dissolution of po...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3350765

Geometry sensing by dendritic cells dictates spatial organization and PGE₂-induced dissolution of podosomes

About this item

Full title

Geometry sensing by dendritic cells dictates spatial organization and PGE₂-induced dissolution of podosomes

Publisher

Basel: Springer-Verlag

Journal title

Cellular and molecular life sciences : CMLS, 2012-06, Vol.69 (11), p.1889-1901

Language

English

Formats

Publication information

Publisher

Basel: Springer-Verlag

More information

Scope and Contents

Contents

Assembly and disassembly of adhesion structures such as focal adhesions (FAs) and podosomes regulate cell adhesion and differentiation. On antigen-presenting dendritic cells (DCs), acquisition of a migratory and immunostimulatory phenotype depends on podosome dissolution by prostaglandin E₂ (PGE₂). Whereas the effects of physico-chemical and topogr...

Alternative Titles

Full title

Geometry sensing by dendritic cells dictates spatial organization and PGE₂-induced dissolution of podosomes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3350765

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3350765

Other Identifiers

ISSN

1420-682X

E-ISSN

1420-9071

DOI

10.1007/s00018-011-0908-y

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