BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice
BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice
About this item
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Author / Creator
Ke, F , Voss, A , Kerr, J B , O'Reilly, L A , Tai, L , Echeverry, N , Bouillet, P , Strasser, A and Kaufmann, T
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
BOK/MTD was discovered as a protein that binds to the anti-apoptotic Bcl-2 family member MCL-1 and shares extensive amino-acid sequence similarity to BAX and BAK, which are essential for the effector phase of apoptosis. Therefore, and on the basis of its reported expression pattern, BOK is thought to function in a BAX/BAK-like pro-apoptotic manner...
Alternative Titles
Full title
BCL-2 family member BOK is widely expressed but its loss has only minimal impact in mice
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3354060
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3354060
Other Identifiers
ISSN
1350-9047
E-ISSN
1476-5403
DOI
10.1038/cdd.2011.210
