Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integratio...
Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Hemoglobinopathies are a collection of heritable diseases caused by abnormal structure or insufficient production of hemoglobins [1]. Many forms of hemo- globinopathies, such as sickle cell disease （SCD） and β-thalassemia, which are caused by mutations of the β-globin （HBB） gene, lead to severe anemia and other life-threatening conditions. Ultimate...
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Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3357996
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3357996
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ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2011.186
