A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A
A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A
About this item
Full title
Author / Creator
Cruz-Migoni, Abimael , Hautbergue, Guillaume M. , Artymiuk, Peter J. , Baker, Patrick J. , Bokori-Brown, Monika , Chang, Chung-Te , Dickman, Mark J. , Essex-Lopresti, Angela , Harding, Sarah V. , Mahadi, Nor Muhammad , Marshall, Laura E. , Mobbs, George W. , Mohamed, Rahmah , Nathan, Sheila , Ngugi, Sarah A. , Ong, Catherine , Ooi, Wen Fong , Partridge, Lynda J. , Phillips, Helen L. , Raih, M. Firdaus , Ruzheinikov, Sergei , Sarkar-Tyson, Mitali , Sedelnikova, Svetlana E. , Smither, Sophie J. , Tan, Patrick , Titball, Richard W. , Wilson, Stuart A. and Rice, David W.
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
Formats
Publication information
Publisher
Washington, DC: American Association for the Advancement of Science
Subjects
More information
Scope and Contents
Contents
A toxin associated with a disease often observed in Vietnam veterans is identified and characterized.
The structure of BPSL1549, a protein of unknown function from
Burkholderia pseudomallei
, reveals a similarity to
Escherichia coli
cytotoxic necrotizing factor 1. We found that BPSL1549 acted as a potent cytotoxin against eukaryotic...
Alternative Titles
Full title
A Burkholderia pseudomallei Toxin Inhibits Helicase Activity of Translation Factor eIF4A
Authors, Artists and Contributors
Author / Creator
Hautbergue, Guillaume M.
Artymiuk, Peter J.
Baker, Patrick J.
Bokori-Brown, Monika
Chang, Chung-Te
Dickman, Mark J.
Essex-Lopresti, Angela
Harding, Sarah V.
Mahadi, Nor Muhammad
Marshall, Laura E.
Mobbs, George W.
Mohamed, Rahmah
Nathan, Sheila
Ngugi, Sarah A.
Ong, Catherine
Ooi, Wen Fong
Partridge, Lynda J.
Phillips, Helen L.
Raih, M. Firdaus
Ruzheinikov, Sergei
Sarkar-Tyson, Mitali
Sedelnikova, Svetlana E.
Smither, Sophie J.
Tan, Patrick
Titball, Richard W.
Wilson, Stuart A.
Rice, David W.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3364511
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3364511
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1211915
