Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts
Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
TGF-β and myostatin are the two most important regulators of muscle growth. Both growth factors have been shown to signal through a Smad3-dependent pathway. However to date, the role of Smad3 in muscle growth and differentiation is not investigated. Here, we demonstrate that Smad3-null mice have decreased muscle mass and pronounced skeletal muscle...
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Full title
Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3364732
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3364732
Other Identifiers
ISSN
1001-0602
E-ISSN
1748-7838
DOI
10.1038/cr.2011.72
