BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfo...
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
About this item
Full title
Author / Creator
Rodriguez, Diego A , Zamorano, Sebastian , Lisbona, Fernanda , Rojas-Rivera, Diego , Urra, Hery , Cubillos-Ruiz, Juan R , Armisen, Ricardo , Henriquez, Daniel R , H Cheng, Emily , Letek, Michal , Vaisar, Tomas , Irrazabal, Thergiory , Gonzalez-Billault, Christian , Letai, Anthony , Pimentel-Muiños, Felipe X , Kroemer, Guido and Hetz, Claudio
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Adaptation to endoplasmic reticulum (ER) stress depends on the activation of the unfolded protein response (UPR) stress sensor inositol‐requiring enzyme 1α (IRE1α), which functions as an endoribonuclease that splices the mRNA of the transcription factor XBP‐1 (X‐box‐binding protein‐1). Through a global proteomic approach we identified the BCL‐2 fam...
Alternative Titles
Full title
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
Authors, Artists and Contributors
Author / Creator
Zamorano, Sebastian
Lisbona, Fernanda
Rojas-Rivera, Diego
Urra, Hery
Cubillos-Ruiz, Juan R
Armisen, Ricardo
Henriquez, Daniel R
H Cheng, Emily
Letek, Michal
Vaisar, Tomas
Irrazabal, Thergiory
Gonzalez-Billault, Christian
Letai, Anthony
Pimentel-Muiños, Felipe X
Kroemer, Guido
Hetz, Claudio
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3364744
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3364744
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.84
