Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of a...
Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition
About this item
Full title
Author / Creator
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Journal title
Language
English
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Publication information
Publisher
Chichester, UK: John Wiley & Sons, Ltd
Subjects
More information
Scope and Contents
Contents
Helix‐loop‐helix (HLH) family transcription factors regulate numerous developmental and homeostatic processes. Dominant‐negative HLH (dnHLH) proteins lack DNA‐binding ability and capture basic HLH (bHLH) transcription factors to inhibit cellular differentiation and enhance cell proliferation and motility, thus participating in patho‐physiological p...
Alternative Titles
Full title
Structure of a dominant-negative helix-loop-helix transcriptional regulator suggests mechanisms of autoinhibition
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3365425
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3365425
Other Identifiers
ISSN
0261-4189
E-ISSN
1460-2075
DOI
10.1038/emboj.2012.77
