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S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3370391

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

About this item

Full title

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2010-12, Vol.468 (7327), p.1115-1118

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

A molecular switch for eNOS
The enzyme eNOS (endothelial nitric oxide synthase) is vital for regulating vascular function as it can produce both the vasodilator nitric oxide and the vasoconstrictor superoxide. Jay Zweier and colleagues show that a modification associated with oxidant stress, S-glutathionylation, switches the enzyme from forming...

Alternative Titles

Full title

S-glutathionylation uncouples eNOS and regulates its cellular and vascular function

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3370391

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3370391

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature09599

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