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Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373730

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

About this item

Full title

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Publisher

London: Nature Publishing Group UK

Journal title

Nature (London), 2011-09, Vol.477 (7364), p.335-339

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Epithelial cell death in intestinal inflammatory disease
Two groups identify the regulation of death-receptor-induced necroptosis as an epithelial intrinsic mechanism that is important for the maintenance of immune homeostasis and the prevention of intestinal inflammation in mice. Welz
et al
. describe an unexpected physiological function...

Alternative Titles

Full title

Caspase-8 regulates TNF-α-induced epithelial necroptosis and terminal ileitis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373730

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3373730

Other Identifiers

ISSN

0028-0836

E-ISSN

1476-4687

DOI

10.1038/nature10400

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