MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing
MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing
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Author / Creator
Moissiard, Guillaume , Cokus, Shawn J. , Cary, Joshua , Feng, Suhua , Billi, Allison C. , Stroud, Hume , Husmann, Dylan , Zhan, Ye , Lajoie, Bryan R. , McCord, Rachel Patton , Hale, Christopher J. , Feng, Wei , Michaels, Scott D. , Frand, Alison R. , Pellegrini, Matteo , Dekker, Job , Kim, John K. and Jacobsen, Steven E.
Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Contents
Transposable elements (TEs) and DNA repeats are commonly targeted by DNA and histone methylation to achieve epigenetic gene silencing. We isolated mutations in two Arabidopsis genes, AtMORC1 and AtMORC6, which cause derepression of DNA-methylated genes and TEs but no losses of DNA or histone methylation. AtMORC1 and AtMORC6 are members of the conse...
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Full title
MORC Family ATPases Required for Heterochromatin Condensation and Gene Silencing
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376212
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3376212
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1221472
