Whole-genome analysis informs breast cancer response to aromatase inhibition
Whole-genome analysis informs breast cancer response to aromatase inhibition
About this item
Full title
Author / Creator
Ellis, Matthew J. , Ding, Li , Shen, Dong , Luo, Jingqin , Suman, Vera J. , Wallis, John W. , Van Tine, Brian A. , Hoog, Jeremy , Goiffon, Reece J. , Goldstein, Theodore C. , Ng, Sam , Lin, Li , Crowder, Robert , Snider, Jacqueline , Ballman, Karla , Weber, Jason , Chen, Ken , Koboldt, Daniel C. , Kandoth, Cyriac , Schierding, William S. , McMichael, Joshua F. , Miller, Christopher A. , Lu, Charles , Harris, Christopher C. , McLellan, Michael D. , Wendl, Michael C. , DeSchryver, Katherine , Allred, D. Craig , Esserman, Laura , Unzeitig, Gary , Margenthaler, Julie , Babiera, G. V. , Marcom, P. Kelly , Guenther, J. M. , Leitch, Marilyn , Hunt, Kelly , Olson, John , Tao, Yu , Maher, Christopher A. , Fulton, Lucinda L. , Fulton, Robert S. , Harrison, Michelle , Oberkfell, Ben , Du, Feiyu , Demeter, Ryan , Vickery, Tammi L. , Elhammali, Adnan , Piwnica-Worms, Helen , McDonald, Sandra , Watson, Mark , Dooling, David J. , Ota, David , Chang, Li-Wei , Bose, Ron , Ley, Timothy J. , Piwnica-Worms, David , Stuart, Joshua M. , Wilson, Richard K. and Mardis, Elaine R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
To correlate the variable clinical features of oestrogen-receptor-positive breast cancer with somatic alterations, we studied pretreatment tumour biopsies accrued from patients in two studies of neoadjuvant aromatase inhibitor therapy by massively parallel sequencing and analysis. Eighteen significantly mutated genes were identified, including five...
Alternative Titles
Full title
Whole-genome analysis informs breast cancer response to aromatase inhibition
Authors, Artists and Contributors
Author / Creator
Ding, Li
Shen, Dong
Luo, Jingqin
Suman, Vera J.
Wallis, John W.
Van Tine, Brian A.
Hoog, Jeremy
Goiffon, Reece J.
Goldstein, Theodore C.
Ng, Sam
Lin, Li
Crowder, Robert
Snider, Jacqueline
Ballman, Karla
Weber, Jason
Chen, Ken
Koboldt, Daniel C.
Kandoth, Cyriac
Schierding, William S.
McMichael, Joshua F.
Miller, Christopher A.
Lu, Charles
Harris, Christopher C.
McLellan, Michael D.
Wendl, Michael C.
DeSchryver, Katherine
Allred, D. Craig
Esserman, Laura
Unzeitig, Gary
Margenthaler, Julie
Babiera, G. V.
Marcom, P. Kelly
Guenther, J. M.
Leitch, Marilyn
Hunt, Kelly
Olson, John
Tao, Yu
Maher, Christopher A.
Fulton, Lucinda L.
Fulton, Robert S.
Harrison, Michelle
Oberkfell, Ben
Du, Feiyu
Demeter, Ryan
Vickery, Tammi L.
Elhammali, Adnan
Piwnica-Worms, Helen
McDonald, Sandra
Watson, Mark
Dooling, David J.
Ota, David
Chang, Li-Wei
Bose, Ron
Ley, Timothy J.
Piwnica-Worms, David
Stuart, Joshua M.
Wilson, Richard K.
Mardis, Elaine R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3383766
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3383766
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11143
