FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mo...
FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality
About this item
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Author / Creator
Shalhoub, Victoria , Shatzen, Edward M , Ward, Sabrina C , Davis, James , Stevens, Jennitte , Bi, Vivian , Renshaw, Lisa , Hawkins, Nessa , Wang, Wei , Chen, Ching , Tsai, Mei-Mei , Cattley, Russell C , Wronski, Thomas J , Xia, Xuechen , Li, Xiaodong , Henley, Charles , Eschenberg, Michael and Richards, William G
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is associated with secondary hyperparathyroidism (HPT) and serum elevations in the phosphaturic hormone FGF23, which may be maladaptive and lead to increased morbidity and mortality. To determine the role of FGF23 in the pathogenesis of CKD-MBD and development of secondary HPT, we developed...
Alternative Titles
Full title
FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3386816
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3386816
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI61405
