HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Key Points
Hypoxia-inducible factor 1α (HIF1α) and HIF2α are broadly expressed in many human cancers, and expression of these proteins frequently correlate with poor patient prognosis.
Although HIF1α and HIF2α share some redundant functions, they also exhibit unique and even opposing activities in cell growth, metabolism, angiogenesis, nitric...
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Full title
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3401912
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3401912
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ISSN
1474-175X
E-ISSN
1474-1768
DOI
10.1038/nrc3183