Block of Kv1.7 potassium currents increases glucose‐stimulated insulin secretion
Block of Kv1.7 potassium currents increases glucose‐stimulated insulin secretion
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Glucose‐stimulated insulin secretion (GSIS) relies on repetitive, electrical spiking activity of the beta cell membrane. Cyclic activation of voltage‐gated potassium channels (K
v
) generates an outward, ‘delayed rectifier’ potassium current, which drives the repolarizing phase of each spike and modulates insulin release. Although several K
Alternative Titles
Full title
Block of Kv1.7 potassium currents increases glucose‐stimulated insulin secretion
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3403299
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3403299
Other Identifiers
ISSN
1757-4676
E-ISSN
1757-4684
DOI
10.1002/emmm.201200218
