Poly (ADP-ribose) transferase/polymerase-1-deficient mice resistant to age-dependent decrease in β-c...
Poly (ADP-ribose) transferase/polymerase-1-deficient mice resistant to age-dependent decrease in β-cell proliferation
About this item
Full title
Author / Creator
Gong, Lei , Liu, Fu-Qiang , Wang, Ying , Hou, Xin-Guo , Zhang, Wei , Qin, Wei-Dong , Zhang, Yun , Chen, Li and Zhang, Ming-Xiang
Publisher
England: BioMed Central
Journal title
Language
English
Formats
Publication information
Publisher
England: BioMed Central
Subjects
More information
Scope and Contents
Contents
Basal and adaptive β-cell regeneration capacity declines with old age, but the underlying molecular mechanisms remain incompletely understood. Poly (adenosine diphosphate [ADP]-ribose) polymerase 1 (PARP-1) is considered a multifunctional enzyme and transcription factor that regulates pancreatic β-cell death, regeneration and insulin secretion. We...
Alternative Titles
Full title
Poly (ADP-ribose) transferase/polymerase-1-deficient mice resistant to age-dependent decrease in β-cell proliferation
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3409279
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3409279
Other Identifiers
ISSN
1076-1551
E-ISSN
1528-3658
DOI
10.2119/molmed.2011.00458
