The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI
The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI
About this item
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Author / Creator
Whalley, H C , Papmeyer, M , Sprooten, E , Romaniuk, L , Blackwood, D H , Glahn, D C , Hall, J , Lawrie, S M , Sussmann, Je and McIntosh, A M
Publisher
London: Nature Publishing Group UK
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Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Genome-wide association studies (GWAS) have demonstrated a significant polygenic contribution to bipolar disorder (BD) where disease risk is determined by the summation of many alleles of small individual magnitude. Modelling polygenic risk scores may be a powerful way of identifying disrupted brain regions whose genetic architecture is related to...
Alternative Titles
Full title
The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3410628
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3410628
Other Identifiers
ISSN
2158-3188
E-ISSN
2158-3188
DOI
10.1038/tp.2012.60